Andrew Huberman
January 29, 2026 · 7 min read
Using Play to Rewire & Improve Your Brain | Huberman Lab Essentials
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Key Takeaways
- 1Welcome to a discussion about one of the most undervalued yet powerful tools for brain development: play.
- 2Much of our childhood development centers around play, whether organized or spontaneous.
- 3The Neurobiology of Play
- 4Play is generated through the connectivity of many brain areas, but one key region is the periaqueductal gray (PAG).
- 5When we engage in play, the PAG releases small amounts of these endogenous opioids into our system.
Overview
Welcome to a discussion about one of the most undervalued yet powerful tools for brain development: play. As a neuroscientist, I want to challenge the common perception that play is merely a childhood activity. The reality is that play serves as a fundamental mechanism for brain plasticity and cognitive enhancement throughout our entire lifespan.
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